Antimicrobials: practice question

A Pharmacology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Pharmacology · Antimicrobials

Sample item

What serious toxicity is associated with chloramphenicol?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

C. Aplastic anaemia

Chloramphenicol can rarely cause idiosyncratic aplastic anaemia and can also cause dose-related marrow suppression, limiting routine use.

Option by option

  • A. Tendon rupture

    Tendon rupture is linked to fluoroquinolones.

  • B. Crystal nephropathy

    Crystal nephropathy has other drug associations.

  • C. Aplastic anaemia (correct)

    Correct: aplastic anaemia is a serious rare toxicity.

  • D. Tooth discoloration

    Tooth staining is linked to tetracyclines.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Pharmacology questions

Questions about this Pharmacology question

What is the answer to this Pharmacology question?

The best answer is C, Aplastic anaemia. Chloramphenicol can rarely cause idiosyncratic aplastic anaemia and can also cause dose-related marrow suppression, limiting routine use.

Why is "Tendon rupture" not the answer?

Tendon rupture is linked to fluoroquinolones.

Why is "Crystal nephropathy" not the answer?

Crystal nephropathy has other drug associations.

Why is "Tooth discoloration" not the answer?

Tooth staining is linked to tetracyclines.

What concept does this question test?

It tests Antimicrobials in Pharmacology. The correct option holds because: Correct: aplastic anaemia is a serious rare toxicity.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Antimicrobials?

Learn drugs as classes, then the exception in each class that an examiner would pick. Then use the flashcards and the other Pharmacology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.