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Anatomy · Thorax: pleura
Sample itemWhich pleural layer is most sensitive to pain from pleurisy?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Parietal pleura
Parietal pleura has somatic sensory innervation and is pain sensitive, whereas visceral pleura is relatively insensitive to pain. Pleuritic pain worsens with respiratory movement.
Option by option
A. Visceral pleura
Visceral pleura lacks the same pain sensitivity.
B. Endocardium
Endocardium lines the heart chambers.
C. Parietal pleura (correct)
Correct. Somatic innervation makes parietal pleura painful.
D. Alveolar epithelium
Alveoli are not the pleural pain source.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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