Neuromuscular blockade: practice question

A Anaesthesia question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Anaesthesia · Neuromuscular blockade

Sample item

What is the major reason succinylcholine is avoided in major burns after 24 hours?

AIt provides no paralysisBRisk of severe hypoglycaemiaCRisk of dangerous hyperkalaemiaDIt causes immediate renal stone

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

C. Risk of dangerous hyperkalaemia

Burns cause upregulation of extrajunctional acetylcholine receptors, so succinylcholine can trigger excessive potassium release and cardiac arrest.

Option by option

A. It provides no paralysis
It remains a paralytic drug.
B. Risk of severe hypoglycaemia
Hypoglycaemia is not the main concern.
C. Risk of dangerous hyperkalaemia (correct)
Correct: receptor upregulation raises potassium-release risk.
D. It causes immediate renal stone
Renal stones are unrelated.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

Questions about this Anaesthesia question

What is the answer to this Anaesthesia question?

The best answer is C, Risk of dangerous hyperkalaemia. Burns cause upregulation of extrajunctional acetylcholine receptors, so succinylcholine can trigger excessive potassium release and cardiac arrest.

Why is "It provides no paralysis" not the answer?

It remains a paralytic drug.

Why is "Risk of severe hypoglycaemia" not the answer?

Hypoglycaemia is not the main concern.

Why is "It causes immediate renal stone" not the answer?

Renal stones are unrelated.

What concept does this question test?

It tests Neuromuscular blockade in Anaesthesia. The correct option holds because: Correct: receptor upregulation raises potassium-release risk.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Neuromuscular blockade?

Make a table of each agent, its key advantage and its main side effect. Then use the flashcards and the other Anaesthesia questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.