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Anaesthesia · Blood management
Sample itemWhat reaction requires immediate stopping of a blood transfusion?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Fever, hypotension, or haemoglobinuria during transfusion
Possible acute transfusion reaction requires stopping transfusion, maintaining intravenous access, checking identification, and initiating urgent investigation and support.
Option by option
A. An unchanged chronic systolic murmur documented before transfusion
A pre-existing unchanged murmur does not indicate an acute transfusion reaction.
B. An oxygen saturation trace unchanged from the pretransfusion baseline
A baseline-equivalent oxygen trace is not by itself a trigger to stop transfusion.
C. Fever, hypotension, or haemoglobinuria during transfusion (correct)
Correct: systemic reaction signs require immediate stop.
D. Localized itch beneath adhesive tape with stable vital signs
Tape-related local itch is not the same as systemic transfusion reaction.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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