Screening: practice question

A PSM question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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PSM · Screening

Sample item

What is lead-time bias in cancer screening?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

D. Earlier diagnosis makes survival from diagnosis appear longer

Lead-time bias occurs when screening advances diagnosis date without changing death date, artificially increasing measured survival after diagnosis.

Option by option

  • A. Test misses true cases

    Missing cases is false-negative error.

  • B. Treatment causes adverse effects

    Adverse effects are screening harms but not lead time.

  • C. Screening detects only harmless disease

    Harmless detection is overdiagnosis.

  • D. Earlier diagnosis makes survival from diagnosis appear longer (correct)

    Correct: earlier clock start creates apparent longer survival.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More PSM questions

Questions about this PSM question

What is the answer to this PSM question?

The best answer is D, Earlier diagnosis makes survival from diagnosis appear longer. Lead-time bias occurs when screening advances diagnosis date without changing death date, artificially increasing measured survival after diagnosis.

Why is "Test misses true cases" not the answer?

Missing cases is false-negative error.

Why is "Treatment causes adverse effects" not the answer?

Adverse effects are screening harms but not lead time.

Why is "Screening detects only harmless disease" not the answer?

Harmless detection is overdiagnosis.

What concept does this question test?

It tests Screening in PSM. The correct option holds because: Correct: earlier clock start creates apparent longer survival.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Screening?

Practise biostatistics with small calculations until sensitivity, predictive values and risk measures are automatic. Then use the flashcards and the other PSM questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.