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Microbiology · Infection control
Sample itemWhy are surgical instruments cleaned before sterilization?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Organic debris can shield microbes from sterilant
Cleaning removes blood, tissue, and organic material that can protect microorganisms and interfere with later disinfection or sterilization.
Option by option
A. Cleaning alone kills all spores
Cleaning alone may not sterilize.
B. Organic debris can shield microbes from sterilant (correct)
Correct: debris reduces sterilization effectiveness.
C. It removes need for packaging
Packaging remains needed to maintain sterility.
D. Sterilization works only on dirty items
Sterilization works best after cleaning.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.