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Pharmacology · Pharmacokinetics
Sample itemWhat does steady state mean during repeated drug dosing?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Rate of drug input equals rate of elimination
At steady state, average drug input over a dosing interval equals elimination, so average plasma concentration becomes stable around a predictable level.
Option by option
A. Rate of drug input equals rate of elimination (correct)
Correct: input and output balance at steady state.
B. All drug is protein bound
Protein binding can vary independently.
C. Drug concentration is zero
Concentration is usually not zero.
D. Absorption is complete
Absorption need not be complete.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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