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Pharmacology · Antibiotics
Sample itemWhat is the major toxicity of linezolid with prolonged use?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Bone-marrow suppression
Linezolid can cause thrombocytopenia and other marrow suppression with prolonged therapy and may also interact with serotonergic medicines.
Option by option
A. Bone-marrow suppression (correct)
Correct: cytopenias require monitoring.
B. Tooth staining
Tooth staining is associated with tetracyclines.
C. Tendon rupture
Tendon rupture is linked to fluoroquinolones.
D. Ototoxicity
Ototoxicity is classic for aminoglycosides.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.