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Anatomy · Embryology: diaphragm
Sample itemA newborn has respiratory distress, a scaphoid abdomen and bowel sounds in the left chest. Failure of which embryonic structure to close explains this defect?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Pleuroperitoneal membrane
A posterolateral Bochdalek hernia results from failure of the pleuroperitoneal membrane to fuse, usually on the left. Abdominal viscera enter the chest, compress the lung and cause pulmonary hypoplasia.
Option by option
A. Dorsal mesentery of the oesophagus
The dorsal mesentery of the oesophagus forms the crura and median part.
B. Septum transversum
The septum transversum forms the central tendon, and its failure causes anterior Morgagni hernias.
C. Body wall mesoderm
Body wall mesoderm contributes peripheral muscle, and defects here are less common.
D. Pleuroperitoneal membrane (correct)
Correct. Failure of fusion leaves a posterolateral defect in the diaphragm.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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