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Physiology · Neurophysiology: cerebellum
Sample itemA patient has a tremor that appears only on reaching for an object and worsens as the finger approaches the target, with past-pointing and dysdiadochokinesia on the right side. Where is the lesion?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Right cerebellar hemisphere
Cerebellar hemispheric lesions cause ipsilateral intention tremor, dysmetria and dysdiadochokinesia, because the cerebellar pathways cross twice and so control the ipsilateral limbs. Basal ganglia lesions cause rest tremor or hemiballismus instead.
Option by option
A. Right cerebellar hemisphere (correct)
Correct. Cerebellar signs are ipsilateral to the lesion.
B. Substantia nigra
Substantia nigra loss causes a resting tremor, rigidity and bradykinesia.
C. Left cerebellar hemisphere
A left lesion would produce signs on the left side of the body.
D. Subthalamic nucleus
A subthalamic lesion causes contralateral hemiballismus.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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