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PSM · Epidemiology
Sample itemA case-control study uses hospitalised patients as both cases and controls and finds a spurious association between two conditions. Which bias is the likely explanation?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Berkson's (admission rate) bias
Berkson's bias arises in hospital-based studies when the probability of admission differs by exposure or disease, so hospital cases and controls differ systematically from the general population. It is a form of selection bias.
Option by option
A. Berkson's (admission rate) bias (correct)
Correct. Differential admission to hospital distorts the comparison.
B. Observer bias
Observer bias results from differences in how outcomes are measured.
C. Recall bias
Recall bias arises from differences in remembering past exposure.
D. Lead-time bias
Lead-time bias belongs to screening and survival comparison.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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