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PSM · Epidemiology: odds ratio
Sample itemIn a case-control study of 100 cases and 100 controls, 40 cases and 20 controls were exposed to a risk factor. What is the odds ratio?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. 2.7
Odds of exposure in cases = 40/60; odds in controls = 20/80. The odds ratio = (40 × 80) / (60 × 20) = 3200 / 1200 ≈ 2.7. A value above 1 suggests a positive association. Relative risk cannot be calculated directly in a case-control design.
Option by option
A. 2.0
This is the ratio of the exposed proportions (40/20), which is not the odds ratio.
B. 0.5
This is the inverse of 2 and does not match the data.
C. 1.5
This value does not follow from the cross-product ratio of the table.
D. 2.7 (correct)
Correct. (40 × 80) ÷ (60 × 20) ≈ 2.7.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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