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Anatomy · Neuroanatomy: medial medullary syndrome
Sample itemAfter a vertebral artery branch occlusion, a man's tongue deviates to the right on protrusion. He has left hemiparesis sparing the face and loss of vibration sense on the left. Which structure explains the tongue deviation?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Right hypoglossal nerve rootlets or nucleus in the medulla
In medial medullary syndrome the hypoglossal fibres, the pyramid and the medial lemniscus are damaged. The tongue deviates toward the side of the lesion because the intact genioglossus on the opposite side pushes it across, producing ipsilateral tongue weakness, contralateral hemiparesis sparing the face, and contralateral loss of vibration and position sense.
Option by option
A. Right glossopharyngeal nerve
The glossopharyngeal nerve supplies taste and sensation to the posterior tongue and stylopharyngeus and does not move the tongue.
B. Right nucleus ambiguus
The nucleus ambiguus supplies pharyngeal and laryngeal muscles, and its lesion causes dysphagia and hoarseness.
C. Right hypoglossal nerve rootlets or nucleus in the medulla (correct)
Damage to the right hypoglossal nerve weakens the right genioglossus, so the left one pushes the tongue to the right.
D. Left hypoglossal nucleus
A left hypoglossal lesion would deviate the tongue to the left.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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