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Anatomy · Embryology: Mullerian duct anomalies
Sample itemA 24-year-old woman has a double uterus with two separate cervices and a longitudinal vaginal septum. Which developmental event failed?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Fusion of the paramesonephric ducts
The paramesonephric (Mullerian) ducts fuse caudally to form the uterovaginal canal and uterus. Total non-fusion gives uterus didelphys with two cervices and often a vaginal septum, whereas partial fusion failure gives bicornuate or septate uteri. Vaginal plate canalisation failure gives vaginal atresia.
Option by option
A. Descent of the gubernaculum
The gubernaculum is involved in gonadal descent and does not form the uterus.
B. Fusion of the paramesonephric ducts (correct)
Correct. Non-fusion of the Mullerian ducts gives uterus didelphys.
C. Canalisation of the vaginal plate
Failure of canalisation of the vaginal plate causes an imperforate hymen or vaginal atresia.
D. Regression of the mesonephric ducts
Persistence of the mesonephric ducts would give Gartner duct remnants.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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