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Anatomy · Abdomen: splenic vein and pancreas
Sample itemA 45-year-old man with chronic pancreatitis has haematemesis. Endoscopy shows gastric fundal varices without oesophageal varices. The spleen is enlarged, and liver function and portal vein flow are normal. Thrombosis of which vessel is the likely cause?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Splenic vein
The splenic vein runs along the posterior surface of the body and tail of the pancreas, so pancreatitis can thrombose it. Splenic blood then drains retrogradely through the short gastric and gastroepiploic veins, producing isolated gastric varices and splenomegaly (left-sided or sinistral portal hypertension). Splenectomy is curative.
Option by option
A. Superior mesenteric vein
Superior mesenteric vein thrombosis causes mesenteric ischaemia, not isolated gastric varices.
B. Inferior mesenteric vein
The inferior mesenteric vein drains into the splenic or superior mesenteric vein, and its occlusion alone would not cause fundal varices.
C. Splenic vein (correct)
Correct. Splenic vein occlusion causes isolated gastric varices with a normal portal vein and liver.
D. Hepatic veins
Hepatic vein thrombosis causes Budd-Chiari syndrome with hepatomegaly and ascites.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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