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Forensic Medicine · Thanatology: post-mortem clot versus thrombus
Sample itemAt autopsy of a woman who died suddenly, a clot in the right ventricle is soft, rubbery, glistening and moulded to the chamber, with a yellow upper layer over a dark red lower layer. It slips out easily without attaching to the endocardium. What does this indicate?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. A post-mortem clot
Post-mortem clots are smooth, glistening, rubbery and conform to the vessel, are not attached to the wall, and often show a yellow chicken-fat layer over a red currant-jelly layer when red cells settle. Ante-mortem thrombi are dry, friable, granular and laminated with lines of Zahn, and they adhere to the wall.
Option by option
A. A post-mortem clot (correct)
Correct. Smooth, rubbery, non-adherent clots with layered colours are post-mortem.
B. An organised old thrombus
Organised thrombi are firmly adherent and fibrous, not soft and rubbery.
C. An ante-mortem mural thrombus
Ante-mortem thrombi are friable, dull, laminated and attached to the vessel wall.
D. A vegetation of infective endocarditis
Vegetations are attached to the valve leaflets and are friable, not moulded clots.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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