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Forensic Medicine · Toxicology: organochlorine poisoning
Sample itemA child is brought with tonic-clonic convulsions after ingesting an endosulfan-containing pesticide. Which step should be avoided in management?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Giving castor oil or other oily purgatives
Organochlorines are lipid soluble, and oils or fats enhance their absorption from the gut, so oily purgatives and fatty foods are avoided. Seizures are controlled with benzodiazepines, the airway protected, and decontamination with charcoal or lavage is done early.
Option by option
A. Benzodiazepines for the seizures
Benzodiazepines are first-line for the seizures.
B. Giving castor oil or other oily purgatives (correct)
Correct. Oily cathartics enhance absorption of lipid-soluble organochlorines.
C. Activated charcoal
Activated charcoal reduces absorption and is acceptable.
D. Gastric lavage after securing the airway
Lavage can be done early once the airway is protected.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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