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Forensic Medicine · Asphyxia: inert gas
Sample itemA man is found dead with a plastic bag over his head connected by a tube to a cylinder of nitrogen. The face is only mildly cyanosed and there are no signs of struggle. Why would he feel little distress before losing consciousness?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Oxygen is displaced but carbon dioxide does not accumulate, so there is no air hunger
The urge to breathe is driven mainly by rising carbon dioxide, not falling oxygen. In an inert gas atmosphere, expired carbon dioxide is washed out, so hypoxia develops without hypercapnia and with little distress, and unconsciousness comes rapidly. Autopsy findings are often non-specific, so circumstances and gas analysis are important.
Option by option
A. Nitrogen binds haemoglobin more strongly than oxygen
Binding to haemoglobin more strongly than oxygen is the mechanism of carbon monoxide, not nitrogen.
B. Oxygen is displaced but carbon dioxide does not accumulate, so there is no air hunger (correct)
Correct. Oxygen lack without carbon dioxide build-up does not provoke air hunger.
C. Nitrogen causes immediate cardiac arrest
Death is from hypoxia, not from direct cardiac poisoning.
D. The gas has a strong sedative action on the brain
Nitrogen is physiologically inert and is not sedative at normal pressure.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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