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Microbiology · Parasitology: Trichomonas vaginalis
Sample itemA 27-year-old woman has frothy greenish malodorous vaginal discharge, vulval itching and a strawberry-appearing cervix. Vaginal pH is 5.5, and wet mount shows motile flagellated pear-shaped organisms. What is the best management?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Oral metronidazole for the patient and her sexual partner
Trichomonas vaginalis is a flagellated protozoon with no cyst stage, transmitted sexually. Oral nitroimidazoles (metronidazole or tinidazole) are used because topical therapy does not reach periurethral and Skene gland reservoirs. Partners must be treated simultaneously to prevent reinfection.
Option by option
A. Oral metronidazole for the patient and her sexual partner (correct)
Correct. Systemic nitroimidazole for both partners clears infection and reinfection.
B. Oral fluconazole for the patient alone
Fluconazole treats candidiasis, which gives curdy discharge with normal pH.
C. Single-dose ceftriaxone with azithromycin
Ceftriaxone with azithromycin treats gonorrhoea and chlamydia, not a protozoon.
D. Topical clotrimazole pessary for the patient and partner
Clotrimazole is an antifungal, and topical agents fail to eradicate trichomoniasis.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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