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Microbiology · Parasitology: Ascaris lumbricoides
Sample itemA 5-year-old rural child has cough, wheeze and transient pulmonary infiltrates with 12% eosinophils. Stool microscopy shows no eggs. What is the most likely explanation?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Larvae are migrating through the lungs, and adult worms have not yet begun laying eggs
In Loeffler syndrome, ingested Ascaris eggs hatch, larvae penetrate the gut, travel to the lungs through the blood, ascend the airway and are swallowed. This takes 1 to 2 weeks and eosinophilic pneumonitis results. Adult worms mature in the small intestine and eggs appear in stool only after about 2 months.
Option by option
A. Ascaris never sheds eggs in stool
Fertilised eggs are shed daily in stool once females mature, and stool microscopy diagnoses established infection.
B. Larvae are migrating through the lungs, and adult worms have not yet begun laying eggs (correct)
Correct. The lung phase precedes egg production by roughly 2 months.
C. Eggs are shed only at night, so the sample missed them
Nocturnal shedding applies to pinworm perianal egg laying and microfilariae in blood, not Ascaris.
D. Adult worms inhabit the bronchi and release eggs in sputum
Adults live in the small intestine, and only larvae pass through the lung.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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