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Microbiology · Mycology: dermatophyte identification
Sample itemA culture from a patient with tinea corporis grows a powdery colony with numerous round microconidia in grape-like clusters and spiral hyphae. Urease is positive and the in vitro hair perforation test is positive. Which species is most likely?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Trichophyton mentagrophytes
Trichophyton mentagrophytes forms clusters of round microconidia, spiral hyphae, a positive urease test and a positive hair perforation test. Trichophyton rubrum, in contrast, usually has a red reverse pigment, few microconidia and a negative hair perforation test. Microsporum species form spindle-shaped macroconidia, and Epidermophyton has club-shaped macroconidia.
Option by option
A. Epidermophyton floccosum
Epidermophyton produces club-shaped macroconidia with no microconidia.
B. Trichophyton rubrum
T. rubrum typically has red pigment and a negative hair perforation test.
C. Microsporum audouinii
Microsporum species produce spindle-shaped macroconidia and do not infect nails.
D. Trichophyton mentagrophytes (correct)
Grape-like microconidia with spiral hyphae and positive hair perforation identify T. mentagrophytes.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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