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Microbiology · Parasitology: malaria parasite density
Sample itemOn a thick blood film from a febrile patient, 320 asexual malaria parasites are counted against 200 white blood cells. The patient's white cell count is 7500/µL. What is the parasite density?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. 12,000 parasites/µL
Parasite density per microlitre equals parasites counted divided by white cells counted, multiplied by the white cell count per microlitre. Here 320 / 200 = 1.6, and 1.6 x 7500 = 12,000 parasites/µL. When a measured count is unavailable, an assumed count of 8000/µL is used.
Option by option
A. 12,000 parasites/µL (correct)
320/200 x 7500 gives 12,000 parasites/µL.
B. 1,200 parasites/µL
This is a factor of ten too low, from a decimal error in the calculation.
C. 2,400 parasites/µL
This results from dividing by 1000 white cells, which was not the number counted.
D. 48,000 parasites/µL
This results from dividing by 50 white cells, which was not the number counted.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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