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Physiology · Reproduction: neural control of ejaculation
Sample itemAfter retroperitoneal lymph node dissection for a testicular tumour, a man has normal erections and orgasm but ejaculates no semen. Which pathway was most likely damaged?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Sympathetic fibres from T10 to L2 through the hypogastric plexus, which mediate emission
Emission, the movement of sperm and secretions into the prostatic urethra, depends on sympathetic outflow from T10 to L2 through the hypogastric plexus, which also closes the bladder neck. Expulsion is somatic through the pudendal nerve, and erection is parasympathetic. Damage to the sympathetic chain during the operation causes dry ejaculation with preserved erection.
Option by option
A. Genitofemoral nerve, which mediates the cremasteric reflex
The genitofemoral nerve has no role in ejaculation.
B. Sympathetic fibres from T10 to L2 through the hypogastric plexus, which mediate emission (correct)
Interruption of the sympathetic outflow abolishes emission and leaves erection and orgasm intact.
C. Parasympathetic pelvic splanchnic nerves (S2 to S4), which mediate erection
Pelvic splanchnic damage would impair erection, which is preserved here.
D. Pudendal nerve (S2 to S4), which mediates rhythmic expulsion by the bulbospongiosus
Pudendal nerve injury impairs expulsion and the orgasmic contractions, and emission would still occur.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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