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Physiology · Special senses: olfaction
Sample itemAfter a road traffic accident with fracture of the cribriform plate, a young man cannot smell coffee but can sense the pungency of ammonia. Which structures were most likely torn?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Unmyelinated axons of olfactory receptor neurons forming the fila olfactoria
Olfactory receptor neurons are bipolar cells in the olfactory epithelium whose unmyelinated axons pass through the cribriform plate to synapse on mitral cells in the olfactory bulb. Shearing at this site causes anosmia. Ammonia is detected by trigeminal nociceptors, which are preserved.
Option by option
A. Unmyelinated axons of olfactory receptor neurons forming the fila olfactoria (correct)
Correct. These axons cross the cribriform plate and are vulnerable to shearing.
B. Fibres of the chorda tympani
The chorda tympani carries taste from the anterior tongue and does not pass through the cribriform plate.
C. Fibres of the trigeminal nerve
Trigeminal fibres detect irritants such as ammonia, which this patient senses.
D. Axons of mitral cells in the olfactory tract
Mitral cell axons run in the olfactory tract above the cribriform plate and are not damaged by its fracture.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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