Try it
Physiology · Neurophysiology: aphasia
Sample itemAfter a left parietal stroke, a man speaks fluently with occasional wrong-word errors and understands commands, but cannot repeat the phrase 'no ifs, ands or buts'. Which structure is affected?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Arcuate fasciculus connecting Wernicke and Broca areas
Conduction aphasia has fluent speech, intact comprehension and poor repetition with paraphasic errors because the arcuate fasciculus cannot relay information between the receptive and expressive areas. In Broca aphasia speech is non-fluent with intact comprehension, and in Wernicke aphasia speech is fluent with poor comprehension. Transcortical aphasias spare repetition.
Option by option
A. Broca area in the inferior frontal gyrus
Broca damage gives non-fluent, effortful speech.
B. Wernicke area in the posterior superior temporal gyrus
Wernicke damage gives poor comprehension with fluent nonsensical speech.
C. Arcuate fasciculus connecting Wernicke and Broca areas (correct)
Correct. Disconnection between the language areas selectively impairs repetition.
D. Watershed regions around the Broca area
Transcortical motor aphasia from watershed lesions spares repetition.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
More Physiology questions
- Cardiac cycleDuring which phase of the cardiac cycle are all valves closed while ventricular pressure…
- Renal physiologyWhich substance is freely filtered and neither reabsorbed nor secreted, so that its clea…
- RespirationWhich of the following shifts the oxygen–haemoglobin dissociation curve to the right?
- Renal physiologyWhich of the following favours glomerular filtration?