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PSM · Epidemiology: attributable risk percent
Sample itemIn a cohort study, the relative risk of lung cancer among smokers compared with non-smokers is 5. What proportion of lung cancer among the smokers can be attributed to smoking?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. 80%
The attributable risk percent (etiological fraction in the exposed) equals (RR - 1) / RR x 100. With RR = 5 this is 4 / 5 = 80%. It tells how much of the disease in exposed persons would be eliminated if the exposure were removed, assuming a causal relationship.
Option by option
A. 20%
This is 1 / RR, the proportion of disease in the exposed that would have occurred anyway.
B. 80% (correct)
Correct. (5 - 1) / 5 = 0.8, so 80% of cancers in smokers are attributable to smoking.
C. 25%
This is 1 / (RR - 1), which is not a meaningful epidemiological measure here.
D. 400%
This is RR - 1 written as a percentage; the attributable fraction cannot exceed 100%.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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