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PSM · Biostatistics: geometric mean
Sample itemAntibody titres in three vaccinated infants are 2, 8 and 32 (fold dilution values spaced geometrically). Which summary measure is appropriate for such data, and what is its value here?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Geometric mean, 8
Titres and other ratio-type data that grow multiplicatively are summarised by the geometric mean, the nth root of the product. Here the cube root of 2 x 8 x 32 = 512 is 8. The arithmetic mean of 14 is pulled upward by the highest titre.
Option by option
A. Arithmetic mean, 14
The arithmetic mean is 14, but it is distorted by the largest value in multiplicatively spaced data.
B. Harmonic mean, 4.6
The harmonic mean (about 4.6) is used for rates and is not standard for titres.
C. Geometric mean, 8 (correct)
Correct. The cube root of 512 is 8.
D. Mid-range, 17
The mid-range of 17 uses only the extreme values and ignores the rest.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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