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PSM · Communicable diseases: dengue management
Sample itemA 22-year-old man has fever for 5 days that has just settled. He now has abdominal pain, persistent vomiting, cold extremities and bleeding gums. Haematocrit has risen by 25% from baseline, and platelet count is 38,000 per microlitre. What is the most appropriate next step?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Intravenous isotonic crystalloid with close haematocrit and vital monitoring
Defervescence with warning signs and a rising haematocrit marks the critical phase of dengue, in which plasma leakage can progress to shock. Intravenous isotonic crystalloid is given in carefully titrated amounts, and the haematocrit and vitals guide the rate. Platelet transfusion is not given prophylactically, and aspirin and other NSAIDs are avoided because of bleeding risk.
Option by option
A. Aspirin for fever and pain control
Aspirin worsens bleeding and platelet dysfunction; paracetamol is the antipyretic of choice.
B. Intravenous isotonic crystalloid with close haematocrit and vital monitoring (correct)
Correct. Fluid replacement guided by haematocrit treats plasma leakage in the critical phase.
C. Empirical broad-spectrum antibiotics with corticosteroids
Dengue is viral, so antibiotics and steroids do not address plasma leakage.
D. Prophylactic platelet transfusion
Prophylactic platelet transfusion does not prevent bleeding and can cause fluid overload; transfusion is reserved for significant bleeding.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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