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PSM · Cancer: oral submucous fibrosis
Sample itemA 28-year-old man has chewed areca nut sachets for 8 years. He complains of burning with spicy food and difficulty opening the mouth. Examination shows blanched buccal mucosa with palpable fibrous bands and an inter-incisor distance of 20 mm. What is the diagnosis and its public health importance?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Oral submucous fibrosis, a potentially malignant disorder
Oral submucous fibrosis is a chronic fibrosing disorder strongly linked to areca nut chewing, common in India. It causes burning, blanching, fibrous bands and trismus, and carries a significant risk of oral cancer, so cessation counselling and regular oral examination are essential.
Option by option
A. Oral candidiasis, an opportunistic infection
Candidiasis gives removable white plaques, not fibrous bands and blanching.
B. Verrucous carcinoma, an established malignancy with no premalignant phase
Verrucous carcinoma is a warty exophytic malignancy and does not cause diffuse blanching with bands.
C. Tetanus, a vaccine-preventable infection
Tetanus trismus is acute and accompanied by spasms, not a gradual onset with mucosal fibrosis.
D. Oral submucous fibrosis, a potentially malignant disorder (correct)
Correct. The areca nut exposure, blanching, bands and trismus are typical of oral submucous fibrosis.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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