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PSM · Dengue: phases of illness
Sample itemAn 8-year-old boy is on day 5 of dengue fever. His fever has just subsided, but he is now lethargic with abdominal pain and persistent vomiting. The haematocrit is rising and the platelet count has fallen to 40,000 per microlitre. Which phase of the illness is he entering, and what is the main risk?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Critical phase, with plasma leakage that can lead to shock over the next 24 to 48 hours
Plasma leakage in dengue typically begins around defervescence, between days 3 and 7, and defines the critical phase. Warning signs include abdominal pain, persistent vomiting, lethargy and a rising haematocrit with falling platelets. These patients need close monitoring and careful fluid therapy because shock may follow.
Option by option
A. Convalescent phase, with the main risk of fluid overload from reabsorption
Reabsorption of leaked fluid occurs later in convalescence, not when haematocrit is rising.
B. Incubation phase, with no risk of complications
He already has symptoms, so the incubation period has passed.
C. Febrile phase, with the main risk of febrile seizures
The fever has already settled, so this is not the febrile phase.
D. Critical phase, with plasma leakage that can lead to shock over the next 24 to 48 hours (correct)
Defervescence with warning signs and haemoconcentration marks the critical phase with leakage.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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