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General Surgery · Appendix: neuroendocrine tumour
Sample itemA 28-year-old woman has an appendicectomy for acute appendicitis. Histology shows an incidental 8 mm well-differentiated neuroendocrine tumour at the tip, with no mesoappendiceal invasion and clear margins. What is the next step?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. No further surgery, with routine follow-up
Appendiceal carcinoids are usually found incidentally at the tip. Tumours smaller than 1 cm with clear margins and no adverse features have negligible metastatic potential, so appendicectomy alone is curative. Right hemicolectomy is considered for tumours larger than 2 cm, base involvement, positive margins, lymphovascular invasion or nodal disease.
Option by option
A. Octreotide therapy
Somatostatin analogues are for metastatic functional tumours, which this is not.
B. Adjuvant chemotherapy
Chemotherapy has no role in a completely excised small well-differentiated tumour.
C. Right hemicolectomy
Right hemicolectomy is reserved for tumours above 2 cm or with high-risk features, none of which are present.
D. No further surgery, with routine follow-up (correct)
Small tip tumours with clear margins are cured by the appendicectomy already done.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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