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General Surgery · Portal hypertension: refractory variceal bleeding
Sample itemA 48-year-old cirrhotic man with acute oesophageal variceal haemorrhage continues to bleed despite terlipressin, prophylactic antibiotics and two sessions of endoscopic band ligation. He is resuscitated and intubated. What is the most appropriate next intervention?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Rescue transjugular intrahepatic portosystemic shunt
Bleeding that persists despite combined pharmacological and endoscopic therapy is refractory variceal bleeding. A balloon tamponade tube can bridge briefly, but rescue TIPS decompresses the portal system and is the recommended definitive rescue. Surgical shunts are reserved for selected patients when TIPS is unavailable.
Option by option
A. Rescue transjugular intrahepatic portosystemic shunt (correct)
Correct. Rescue TIPS lowers portal pressure and controls refractory bleeding.
B. Repeat the same band ligation indefinitely
Repeating a failed modality without lowering portal pressure is unlikely to stop the bleed.
C. Increase oral propranolol dose
Oral beta-blockers are used for secondary prophylaxis, not for acute uncontrolled haemorrhage.
D. Oesophagectomy
Oesophagectomy is a major operation with prohibitive mortality in a cirrhotic bleeding patient.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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