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General Surgery · Liver: pyogenic abscess organism
Sample itemA 54-year-old diabetic man has fever and a solitary 6 cm right lobe liver abscess. Aspirated pus is thick and yellow, and culture grows a mucoid lactose-fermenting Gram-negative bacillus. Three days later he complains of eye pain and blurred vision. Which organism is most likely?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Klebsiella pneumoniae
Hypervirulent Klebsiella pneumoniae is a leading cause of cryptogenic pyogenic liver abscess in diabetic patients in Asia and is notable for metastatic spread, especially endophthalmitis and meningitis. Management is percutaneous drainage plus intravenous antibiotics, with urgent ophthalmic assessment if eye symptoms appear.
Option by option
A. Entamoeba histolytica
Entamoeba gives sterile anchovy-sauce pus with no bacteria on culture.
B. Echinococcus granulosus
Echinococcus is a tapeworm cyst that would not grow on routine bacterial culture.
C. Klebsiella pneumoniae (correct)
Correct. A mucoid lactose-fermenting bacillus with abscess and endophthalmitis in a diabetic suggests Klebsiella.
D. Staphylococcus aureus
Staphylococcus aureus is a Gram-positive coccus, causing multiple abscesses in children or after bacteraemia.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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