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Anaesthesia · Preoperative assessment: recent coronary stent and antiplatelets
Sample itemA 62-year-old man had a drug-eluting coronary stent placed three months ago and takes aspirin and clopidogrel. He now needs an urgent laparotomy for a perforated viscus. What is the most appropriate antiplatelet plan?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Continue aspirin and decide on clopidogrel jointly with the cardiologist and surgeon
Stopping antiplatelet therapy early after a drug-eluting stent carries a high risk of stent thrombosis, so aspirin is continued whenever possible. The decision about the P2Y12 inhibitor balances stent thrombosis against surgical bleeding and is made with the cardiologist and surgeon. An urgent operation cannot be postponed.
Option by option
A. Continue aspirin and decide on clopidogrel jointly with the cardiologist and surgeon (correct)
Correct. Aspirin is continued, and the P2Y12 inhibitor is a shared risk-benefit decision.
B. Stop aspirin but continue clopidogrel alone through surgery
Aspirin is the drug that is usually kept, so continuing clopidogrel alone reverses the priority.
C. Stop both drugs now and give prophylactic heparin as cover for the stent
Heparin does not protect a stent from thrombosis, so stopping both agents leaves it unprotected.
D. Stop both drugs and delay the operation by a week to restore platelet function
A perforated viscus needs urgent surgery, and waiting a week would be harmful and unnecessary.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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