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Anaesthesia · Complications and emergencies: stress ulcer prophylaxis
Sample itemWhich pair are the major independent risk factors for clinically important gastrointestinal bleeding in intensive care, and so the main indications for stress ulcer prophylaxis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Ventilation for over 48 hours and coagulopathy
Prolonged mechanical ventilation and coagulopathy were the strongest risk factors for significant bleeding. Prophylaxis is given with a proton pump inhibitor or H2 blocker in such patients, and early enteral feeding is protective.
Option by option
A. Enteral feeding and a low serum albumin
Enteral feeding is protective rather than harmful.
B. Obesity and long-standing hypertension
Obesity and hypertension do not define stress ulcer risk.
C. Ventilation for over 48 hours and coagulopathy (correct)
Correct. These two identify patients who benefit from prophylaxis.
D. Age above 60 years and diabetes mellitus
Age and diabetes are not the key independent risk factors for bleeding.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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