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Anatomy · General anatomy and histology: muscle fibre types
Sample itemA marathon runner's muscle biopsy is stained for myoglobin and oxidative enzymes. Most fibres are dark, rich in mitochondria and capillaries, slow to contract and highly resistant to fatigue. What are these fibres?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Type I (slow oxidative)
Type I fibres are red, slow-twitch and oxidative, suited to sustained postural and endurance work. Type IIb fibres are pale, fast and fatigable, while type IIa are intermediate. Intrafusal fibres belong to the muscle spindle and are not force-generating fibres.
Option by option
A. Intrafusal nuclear bag fibres
Intrafusal fibres are sensory-regulating spindle fibres, not the bulk of the muscle.
B. Type IIb (fast glycolytic)
Type IIb fibres are pale, glycolytic and fatigue quickly.
C. Type I (slow oxidative) (correct)
Correct. High myoglobin, mitochondria and fatigue resistance define slow oxidative fibres.
D. Type IIa (fast oxidative-glycolytic)
Type IIa fibres are fast and only moderately fatigue resistant.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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