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Forensic Medicine · Toxicology: Calotropis poisoning
Sample itemA woman applies the milky latex of a roadside shrub with large oval leaves and pale purple flowers to induce an abortion. She develops vomiting, bradycardia, hyperkalaemia and atrioventricular block. Which plant is most likely?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Calotropis
Calotropis latex contains cardiac glycosides, including calotropin, and is also an irritant. It is used in India to procure abortion and for infanticide. Toxicity resembles digoxin poisoning, with nausea, bradycardia, conduction block and hyperkalaemia.
Option by option
A. Calotropis (correct)
Correct. A glycoside-containing milky latex explains the digoxin-like picture.
B. Datura
Datura causes an anticholinergic syndrome with tachycardia and dry skin.
C. Abrus precatorius
Abrus seeds contain abrin and cause gastroenteritis and organ failure, not a digoxin-like picture.
D. Ricinus communis
Castor seeds contain ricin and cause gastroenteritis and vascular collapse, not heart block.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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