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Microbiology · Virology: Chandipura virus
Sample itemDuring the monsoon, children in central and western India present with high fever, vomiting and rapidly progressive encephalitis with high mortality. The virus is a bullet-shaped RNA virus spread by sandflies. Which virus is responsible?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Chandipura virus
Chandipura virus is a vesiculovirus in the Rhabdoviridae family, and it is transmitted by phlebotomine sandflies. It has caused outbreaks of acute encephalitis in children in parts of India, and there is no specific treatment.
Option by option
A. Chandipura virus (correct)
Correct. A sandfly-transmitted rhabdovirus causing paediatric encephalitis is Chandipura virus.
B. Rabies virus
Rabies virus is also bullet-shaped but spreads by animal bite and not by sandflies.
C. Japanese encephalitis virus
Japanese encephalitis virus is a flavivirus carried by Culex mosquitoes.
D. Nipah virus
Nipah virus is a paramyxovirus spread from bats via fruit, palm sap or contact.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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