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Microbiology · Mycology: Cryptococcus gattii
Sample itemAn immunocompetent farmer from an area with eucalyptus trees has a pulmonary mass and meningitis with a large cryptococcoma on MRI. Which species is most likely?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Cryptococcus gattii
Cryptococcus gattii is associated with eucalyptus and other trees and affects immunocompetent hosts, often forming large mass lesions called cryptococcomas. C. neoformans is associated with pigeon droppings and chiefly affects immunocompromised patients.
Option by option
A. Cryptococcus gattii (correct)
Correct. Eucalyptus exposure and cryptococcoma in a healthy host indicate C. gattii.
B. Histoplasma capsulatum
Histoplasma is a small intracellular yeast associated with bat or bird droppings and does not have a capsule.
C. Candida albicans
Candida albicans is a yeast with pseudohyphae and does not form such mass lesions with meningitis.
D. Cryptococcus neoformans var. grubii
C. neoformans grubii usually causes meningitis in people with HIV or transplant, linked to pigeon droppings.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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