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General Surgery · Gastrointestinal surgery: diffuse oesophageal spasm
Sample itemA 45-year-old has intermittent chest pain and dysphagia for both solids and liquids. Barium swallow shows a corkscrew oesophagus, and manometry shows simultaneous contractions with normal lower oesophageal sphincter relaxation. What is the diagnosis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Diffuse oesophageal spasm
Diffuse oesophageal spasm is a motility disorder with premature or simultaneous contractions that cause a corkscrew or rosary-bead barium appearance and chest pain mimicking angina. Lower sphincter relaxation is normal, which separates it from achalasia. Treatment includes calcium channel blockers or nitrates, and myotomy for refractory cases.
Option by option
A. Systemic sclerosis of the oesophagus
Systemic sclerosis gives a hypotensive sphincter and absent peristalsis with reflux, not simultaneous contractions.
B. Peptic oesophageal stricture
A peptic stricture gives progressive dysphagia to solids with long-standing reflux and a smooth narrowing.
C. Achalasia cardia
Achalasia has absent peristalsis and incomplete lower sphincter relaxation, with a bird's beak appearance.
D. Diffuse oesophageal spasm (correct)
Correct. Simultaneous contractions with intact sphincter relaxation define diffuse oesophageal spasm.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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