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Anaesthesia · Intravenous and inhalational agents: tube cuff pressure with nitrous oxide
Sample itemDuring a three-hour anaesthetic with 66 percent nitrous oxide, the pilot balloon feels tighter and cuff pressure is above 40 cm H2O. What is the explanation?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Nitrous oxide diffuses into the air-filled cuff, increasing its volume and pressure
Nitrous oxide diffuses into the air-filled cuff faster than nitrogen diffuses out, so cuff pressure rises and can exceed capillary perfusion pressure of the tracheal mucosa. Cuff pressure is monitored and kept at 20 to 30 cm H2O, or the cuff is filled with the gas mixture.
Option by option
A. Warming of the tube softens it and tightens the cuff
Warming the tube does not significantly raise the pressure.
B. Nitrous oxide diffuses into the air-filled cuff, increasing its volume and pressure (correct)
Correct. Inward diffusion of nitrous oxide expands the cuff.
C. The tube has migrated into a bronchus
Bronchial migration affects ventilation, not the cuff pressure.
D. Airway secretions are compressing the cuff
Secretions outside the cuff do not change the pressure within it.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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