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Anaesthesia · Intravenous and inhalational agents: ventilation and rise in alveolar concentration
Sample itemDuring inhalational induction with a blood-soluble volatile agent, how does increasing alveolar ventilation affect the rate of rise of alveolar concentration?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. It makes the rise faster
Greater alveolar ventilation delivers the agent to the alveoli faster and replaces what blood has removed. The effect is most obvious for soluble agents, where uptake is large and ventilation limits the rise.
Option by option
A. It makes the rise slower, because pulmonary vessels dilate
Hyperventilation does not dilate pulmonary vessels in a way that slows the rise.
B. It has no effect, as only solubility matters
Solubility is important, but ventilation also determines the rise, particularly for soluble agents.
C. It makes the rise slower, because more agent is washed out
Ventilation delivers the agent; it does not wash out the inspired concentration during induction.
D. It makes the rise faster (correct)
Correct. Faster delivery of the agent to the alveoli speeds the rise, especially for soluble agents.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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