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Dentistry · Caries, pulp and periodontal disease: antimicrobial in necrotising gingivitis
Sample itemA young stressed smoker has painful, bleeding gingiva with punched-out papillae, a grey pseudomembrane, foul breath and low-grade fever. After local debridement, which drug is most appropriate for the systemic infection?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Metronidazole
Necrotising gingivitis is associated with fusiform bacteria, spirochaetes and other anaerobes. Debridement, oral hygiene and metronidazole, which is active against anaerobes, are the usual treatment, with stress and smoking addressed.
Option by option
A. Metronidazole (correct)
Correct. Metronidazole targets the anaerobic flora of necrotising disease.
B. Acyclovir
Acyclovir treats herpes viruses, and the picture here is not a herpetic gingivostomatitis.
C. Fluconazole
Fluconazole is an antifungal and the lesion is bacterial.
D. Gentamicin
Gentamicin has little activity against anaerobes and is not used in this setting.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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