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Dentistry · Oral medicine and oral cancer: erythema multiforme
Sample itemA young man develops painful haemorrhagic, crusted lips and widespread oral erosions a week after a cold sore. He also has target-shaped lesions on the palms. What is the likely diagnosis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Erythema multiforme
Erythema multiforme is a hypersensitivity reaction commonly triggered by herpes simplex or drugs. It produces target lesions on the skin, with bloody, crusted lips and mucosal erosions, and it is self-limiting in the minor form.
Option by option
A. Primary herpetic gingivostomatitis
Primary herpetic gingivostomatitis is a first-exposure infection in young children with gingival swelling.
B. Pemphigus vulgaris
Pemphigus vulgaris does not produce targetoid lesions and runs a chronic course.
C. Behcet disease
Behcet disease features recurrent oral and genital ulcers and uveitis rather than target lesions.
D. Erythema multiforme (correct)
Correct. Target lesions with haemorrhagic crusted lips after herpes simplex point to erythema multiforme.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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