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General Surgery · Hepatobiliary and pancreatic surgery: serous cystadenoma
Sample itemA 55-year-old woman has an incidental 4 cm pancreatic cyst. CT shows a cluster of many tiny cysts with a central stellate scar and calcification. Cyst fluid is low in CEA. What is the diagnosis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Serous cystadenoma
Serous cystadenoma is a benign lesion composed of numerous small glycogen-rich cysts with a central scar. It can be observed unless symptomatic. Mucinous cystic neoplasms are larger unilocular or septated cysts with high CEA and malignant potential.
Option by option
A. Pancreatic pseudocyst
A pseudocyst follows pancreatitis and has no scar or microcystic architecture.
B. Mucinous cystic neoplasm
Mucinous cystic neoplasms are macrocystic with high CEA and ovarian-type stroma.
C. Serous cystadenoma (correct)
Correct. A microcystic honeycomb with a central scar and low CEA is typical.
D. Solid pseudopapillary neoplasm
Solid pseudopapillary tumours are solid-cystic masses in young women.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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