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General Surgery · Hepatobiliary and pancreatic surgery: recurrent pyogenic cholangitis
Sample itemA 40-year-old woman from East Asia has repeated episodes of cholangitis. Imaging shows dilated intrahepatic ducts of the left lateral segment and right posterior sector filled with soft stones. Which type of stone is typical of this condition?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Brown pigment stones
Recurrent pyogenic cholangitis is associated with biliary parasitic infestation and bacterial infection. Bacterial beta-glucuronidase deconjugates bilirubin, forming soft brown pigment stones within intrahepatic and extrahepatic ducts, with strictures and repeated cholangitis.
Option by option
A. Pure cholesterol stones
Cholesterol stones form in the gallbladder from supersaturated bile.
B. Brown pigment stones (correct)
Correct. Infected, stagnant bile produces soft brown pigment stones.
C. Black pigment stones
Black stones are associated with chronic haemolysis and cirrhosis, not duct infection.
D. Calcium carbonate stones
Calcium carbonate stones are rare and associated with limy bile.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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