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Microbiology · Parasitology: Brugia malayi microfilaria
Sample itemA blood film taken at night in Kerala shows sheathed microfilariae about 220 micrometres long, with two discrete nuclei at the tail tip. Which species is it?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Brugia malayi
Brugia malayi microfilariae are sheathed, with two separate nuclei at the tail tip, and are nocturnally periodic in the classic form. W. bancrofti has a tail free of nuclei, and Loa loa has nuclei running to the tip.
Option by option
A. Wuchereria bancrofti
W. bancrofti microfilariae have a clear tail without nuclei at the tip.
B. Loa loa
Loa loa is a daytime-periodic microfilaria with nuclei continuous to the tail tip.
C. Brugia malayi (correct)
Correct. Two discrete terminal nuclei in a sheathed nocturnal microfilaria indicate Brugia malayi.
D. Mansonella perstans
Mansonella perstans microfilariae are unsheathed and nonperiodic.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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