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Microbiology · Parasitology: cryptosporidiosis treatment
Sample itemAn immunocompetent child has watery diarrhoea for a week after swimming in a pool. A modified acid-fast stain shows 4 to 6 micrometre oocysts in stool. Which drug is the treatment of choice?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Nitazoxanide
Cryptosporidiosis is usually self-limiting in immunocompetent hosts, but nitazoxanide is the drug used for treatment. In HIV, immune restoration with antiretroviral therapy is the key.
Option by option
A. Albendazole
Albendazole acts on nematodes and some cestodes, not on Cryptosporidium.
B. Metronidazole
Metronidazole is not effective against Cryptosporidium.
C. Praziquantel
Praziquantel acts on trematodes and cestodes, not on protozoa.
D. Nitazoxanide (correct)
Correct. Nitazoxanide is the drug used against Cryptosporidium.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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