Try it
Physiology · Respiratory system: absorption atelectasis
Sample itemA post-operative patient is given 100 percent oxygen for many hours. A segmental bronchus is partly obstructed by secretions, and the lung volume of that segment gradually falls. Why does breathing pure oxygen predispose to this?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Oxygen is absorbed into the blood faster than it is replaced, and no nitrogen remains to splint the alveoli open
In an alveolus supplied by a narrowed airway, oxygen leaves into the blood faster than inspired gas replaces it. When the inspired gas is mostly nitrogen, this poorly absorbed gas stays behind and keeps the alveolus open; with pure oxygen the gas is fully absorbed and the unit collapses.
Option by option
A. Pure oxygen causes bronchospasm of the obstructed segment
Bronchospasm is not the mechanism of absorption atelectasis.
B. High oxygen tension inhibits ciliary beating and stops all gas flow
Reduced ciliary function does not abolish gas flow and is not the principal mechanism.
C. Oxygen is absorbed into the blood faster than it is replaced, and no nitrogen remains to splint the alveoli open (correct)
Correct. Without a poorly absorbed nitrogen splint, the alveolar gas is absorbed and the unit collapses.
D. Pure oxygen destroys surfactant in all alveoli at once
Oxygen does not destroy surfactant across all alveoli immediately, and the problem is local to a narrowed airway.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
More Physiology questions
- Cardiac cycleDuring which phase of the cardiac cycle are all valves closed while ventricular pressure…
- Renal physiologyWhich substance is freely filtered and neither reabsorbed nor secreted, so that its clea…
- RespirationWhich of the following shifts the oxygen–haemoglobin dissociation curve to the right?
- Renal physiologyWhich of the following favours glomerular filtration?