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Physiology · Neurophysiology and special senses: vestibular hair cell response
Sample itemIn a semicircular canal, what happens when the stereocilia of a hair cell bend towards the kinocilium?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. The cell depolarises and afferent firing increases
Bending towards the kinocilium opens mechanically gated channels and depolarises the hair cell, increasing transmitter release and firing in the vestibular nerve. Bending away hyperpolarises the cell and reduces firing.
Option by option
A. The cell depolarises and afferent firing increases (correct)
Correct. Bending towards the kinocilium depolarises the cell and increases firing.
B. The cell depolarises and afferent firing stays unchanged
Depolarisation increases transmitter release and therefore the firing rate.
C. The cell hyperpolarises and afferent firing decreases
This describes bending away from the kinocilium.
D. The cell hyperpolarises and afferent firing increases
Hyperpolarisation reduces transmitter release, so firing cannot increase.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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